Amy K. Wagner, MD

Associate Professor and Director Translational Research, UPMC Endowed Chair Translational Research, Physical Medicine and Rehabilitation Associate Director Rehabilitation Research, Safar Center for Resuscitation Research Training Faculty, Center for Neuroscience at the University of Pittsburgh

Rehabilomics Research:  Biomarkers based approaches to precision rehabilitation care for TBI

To date, nearly every area of medicine uses biomarkers in some capacity to aid in understanding how personal biology informs clinical care. The NIH precision medicine initiative has propelled biomarkers research to the forefront of many translational research and care programs targeting specific disease based populations. Approaches by which to assess the utility of ‘omics research in the context of acquired disability is a relatively understudied area, yet precision care needs are important to consider as disability contributes an additional layer of potential biological impacts and factors which affect health and function.  This session will overview recent advances in Rehabilomics research that is focused on linking personal biology to the biopsychosocial constructs that represent WHO-ICF model and multidimensional outcome for individuals with TBI.  A roadmap for scaling and translating Rehabilomics research findings into precision rehabilitation care initiatives for individuals with TBI will be discussed.

Presenter Bio:

Amy K. Wagner, MD, is a tenured Associate Professor, Vice-chair Faculty Development, and Endowed Chair for Translational Research in the Department of Physical Medicine and Rehabilitation at the University of Pittsburgh.  She holds a secondary appointment in the Department of Neuroscience and is Associate Director for Rehabilitation Research at the Safar Center for Resuscitation Research.  Dr. Wagner’s research program uses biomarkers as tools for developing and optimizing personalized treatments and outcomes for individuals with disability, particularly TBI.  She has defined her work with rehabilitation centered biomarkers research as Rehabilomics Researc. Dr. Wagner directs a NIDILRR funded TBI Model System of Research and Care Excellence whose research focus includes the TBI Rehabilomics Research Model.  Her experimental research also focuses on how agents commonly used during rehabilitation impact recovery.  Dr. Wagner has published over 90 original research and 35 invited articles.  She mentored dozens of trainees, many of which have received awards and scholarships for their research. She is Training Faculty for the Center for Neuroscience at the University of Pittsburgh. Clinically, Dr. Wagner treats patients with neurological conditions undergoing inpatient rehabilitation, and she is a consultant for neurologically devastated patients during their acute hospitalization at the University of Pittsburgh Medical Center.